Background

Single anastomosis duodenoileostomy with sleeve gastrectomy(SADI-S) is an emerging hypoabsorptive metabolic and bariatric surgery (MBS) procedure. The available literature demonstrates that the procedure is safe and effective, with promising metabolic and bariatric effects. However, there is a gap in knowledge about the impact of Obstructive Sleep Apnea (OSA) on the morbidity and mortality associated with the SADI-S procedure

Methods

Patients who underwent primary SADI-S within the MBSAQIP database from January 1, 2020, to December 31, 2021, were included to compare 30-day outcomes between OSA versus no-OSA patients

Results

A total of 527 patients were included. 278 and 249 in the no-OSA and OSA groups, respectively. Patients with OSA had a higher rate of type 2 diabetes (37.3 % vs. 25.5%, p=0.003), COPD (3.2 % vs. 0.0%, p=0.003), GERD (30.9 % vs. 18.3%, p<0.001), hypertension (66.7 % vs. 39.6%, p<0.001), and hyperlipidemia (34.5% vs. 17.6%, p<0.001) compared to patients without OSA. In addition, patients with OSA had more blood transfusions (3.2 % vs 0.4%, p=0.012) than patients without OSA. However, there were no statistically significant differences between groups regarding mortality, anastomotic leak, operative time, readmissions, reoperations, and unplanned admissions to ICU

Conclusions

Patients who underwent SADI-S with a history of OSA have similar 30-day postoperative outcomes compared to patients without a history of OSA.These results may imply that SADI-S is a safe and feasible procedure in patients with a history of OSA. Additional studies with more patients and, with a prospective design, are needed to validate this conclusion.